Which of the medications would most likely potentiate or elevate serum digoxin levels?

The following medications were noted on review of the client’s home medication profile.

Which of the medications would most likely potentiate or elevate serum digoxin levels?
A . KCl
B . Thyroid agents
C . Quinidine
D . Theophylline

View Answer

Answer: C

Explanation:

(A) Hypokalemia can cause digoxin toxicity. Administration of KCl would prevent this.

(B) Thyroid agents decrease digoxin levels.

(C) Quinidine increases digoxin levels dramatically.

(D) Theophylline is not noted to have an effect on digoxin levels.