Posted by: Pdfprep
Post Date: February 7, 2021
Which of the following factors would be important in determining the concentration of drug that would be reached in the cerebrospinal fluid for treatment of meningitis?
I. Oil/water partition coefficient
II. Binding to plasma protein
III. pKa of the drug
A . I only
B . III only
C . I and II only
D . II and III only
E . I, II and III
Answer: E